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Tekle-Smith Lab

Colorful Book Spines

Publications

2024

2. “Synthesis of the auxin analog 5-Ph-IAA for conditional protein depletion in C. elegans using the AID2 system” Sural, S.; Botero, J. Q.; Hobert, O.*; Tekle-Smith, M. A.* STAR Protocols. 2024, 5, 102901. [DOI: 10.1016/j.xpro.2024.102901]

2023

“Strategies for Nucleophilic C(sp3)–(Radio)Fluorination” Leibler, I. N.-M.; Gandhi, S. S.; Tekle-Smith, M. A.; Doyle A. G. J. Am. Chem. Soc. 2023. [DOI: 10.1021/jacs.3c01824]

Prior Publications

2021

5. N-Acetoxyphthalimide. Leibler, I. N.-M.; Tekle-Smith, M. A. Encyclopedia of Reagents for Organic Synthesis; John Wiley & Sons, Ltd: Chichester, United Kingdom, 2021.

4. A General Strategy for C(sp3)–H Functionalization with Nucleophiles Using Methyl Radical as a Hydrogen Atom Abstractor. Leibler, I. N.-M. *; Tekle-Smith, M. A.*; Doyle, A. G. Nat. Commun. 2021, 12, 6950.

Previously on ChemRxiv

2020

3. Nickel/Photoredox-Catalyzed Methylation of (Hetero)aryl Chlorides Using Trimethyl Orthoformate as a Methyl Radical Source. Kariofillis, S. K.; Shields, B. J.*; Tekle-Smith, M. A.*; Zacuto, M. J.; Doyle, A. G. J. Am. Chem. Soc. 2020, 142, 16, 7683–7689.

2018

2. Design, 22-step synthesis, and evaluation of highly potent linker-equipped analogs of spongistatin 1. Suen, L. M.; Tekle-Smith, M. A.; Williamson, K. S.; Infantine, J. R.; Reznik, S. K.; Tanis, P. S.; Casselman, T. D.; Sackett, D. L.; Leighton, J. L. Nat. Commun. 2018, 9, 4710.

2017

1. Direct, Mild, and General n-Bu4NBr-Catalyzed Aldehyde Allylsilylation with Allyl Chlorides. Tekle-Smith, M. A.; Williamson, K. S.; Hughes, I. F.; Leighton, J. L. Org. Lett. 2017, 19, 6024–6027.

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